When I first came across Hers Weight Loss, I was deep in one of those social media scrolls we sometimes get trapped in. I’ve had my fair share of postpartum body struggles, sugar cravings, and the constant mental chatter about food. So when I saw how many people were praising the Hers program for helping them lose weight fast and control their appetite, I decided to give it a try.
I ordered Kit 1 from the official Hers website, curious but hopeful. My goal wasn’t unrealistic. I just wanted to lose about 20 to 30 pounds, feel lighter, and regain some confidence.
Now that I’ve completed my first kit and gone through all the ups and downs, I want to share everything. The good, the bad, and the unexpected. Because this isn’t just another review, it’s my lived experience.

About Hers Weight Loss
Hers Weight Loss is part of the forhers.com brand. It’s a telehealth company that offers treatments for women in areas like weight management, anxiety, and skincare. The weight loss program is a personalized prescription plan designed to help women lose weight safely through a combination of medications, dietary guidance, and doctor support.
They offer different medication options depending on your health profile. Most people, like me, get a combination that includes Bupropion (an antidepressant), Naltrexone (used for addiction treatment), and Metformin (used for blood sugar control).
The idea behind this combination is to regulate hunger signals, reduce cravings, and balance metabolism. You take the pills daily according to a doctor-supervised plan that gradually increases your dosage over time.
It all sounds very structured and reassuring on paper. But how does it actually feel in real life? That’s where things got complicated for me.
My experience taking Hers Weight Loss pills
I started Kit 1 feeling optimistic. The first two weeks were surprisingly smooth. No major side effects, just a bit of fatigue here and there. My appetite decreased noticeably, which felt like a small victory in itself.

But things started changing quickly in week three, when the medication dose increased and Metformin was added to the mix. That’s when my body began to rebel.
What I didn’t expect
Almost overnight, my stomach turned into a war zone. No matter what I ate, soup, salad, or toast, I would either have extreme diarrhea with awful stomach pains or I’d throw everything up within minutes. There were days I’d have to run to the bathroom multiple times, barely keeping water down.
I told myself it was just an adjustment phase, but by week eight the side effects had become unbearable.
I started experiencing constant acid reflux, so bad that I now carry Tums everywhere I go. I felt drowsy, mentally foggy, and my once bright and bubbly self started fading into someone I barely recognized. I was sluggish, anxious, and emotionally flat. That “blah” feeling crept in and dulled everything.
At work, my coworkers even started asking if I was okay because I seemed off. One of them gently asked if I had started taking antidepressants, and that moment really made me pause.
Before Hers, I was in a good place mentally. Busy, sure, but happy. After a few weeks on the medication, I noticed my anxiety rising and my mood sinking for no obvious reason. I’d lose focus easily, forget small tasks, and feel too sleepy to concentrate.
When I reached out to the Hers doctor through chat, they were kind and responsive. They suggested I lower the dosage until the side effects improved, which I did. It helped a little, but the brain fog and fatigue never fully went away.
What’s in the pills?
One night, while venting about how I was feeling, my husband asked what meds were actually in the pills. When I mentioned Naltrexone, he froze.
He has a cousin who is a recovering heroin addict, clean for years now, and he recognized that name immediately. Naltrexone, he explained, is a medication used to help people overcome drug addiction by blocking the effects of opioids. He told me how it had made his cousin depressed back then and even put some of his peers on suicide watch in rehab.
That conversation shook me.
I started doing deeper research and realized that while Naltrexone can help curb cravings, which explains why my food urges disappeared, it can also trigger low mood, fatigue, and emotional numbness in some people. Suddenly, all my symptoms made sense.
I realized I might have been treating my weight, but I was compromising my mental health in the process.
Safer and Gentler Alternatives
If you want to lose weight but don’t want to risk these kinds of side effects, there are safer options to explore.
Amazon.com has top-rated appetite control options such as Apple Cider Vinegar Capsules that are far gentler on the body.
You can rely on balanced nutrition and accountability apps like Noom or MyFitnessPal. They help you track calories and build better food habits.
Is Hers Weight Loss FDA Approved?
The Hers Weight Loss program itself isn’t FDA approved as a whole because it’s a telehealth service. However, the individual medications they prescribe, such as Bupropion, Naltrexone, and Metformin, are all FDA approved for other medical uses.
The combination of these drugs for weight loss is what’s called an off-label use. That means doctors can legally prescribe them for this purpose, but the FDA hasn’t officially approved them as a combined treatment for weight loss.
So while the ingredients are regulated, the overall program isn’t something the FDA has specifically evaluated for safety and effectiveness.
Is Hers weight loss pills Safe?
Safety really depends on your personal health, medical history, and tolerance to medications.
For some women, especially those who don’t react strongly to prescription drugs, Hers can be safe and effective when used under medical supervision. But for others, especially those with digestive issues, anxiety, or depression, it may trigger unpleasant or even harmful side effects.
In my case, the constant stomach issues, fatigue, and mood swings made it feel far from safe. I also learned that some of the medications used, like Naltrexone, can interact with other prescriptions or intensify certain mental health symptoms.
If you’re considering Hers, I strongly recommend consulting your personal doctor first and discussing all potential risks, especially if you’re taking other medications or have a history of depression or anxiety.
Pros
- Suppressed my appetite effectively
- Curbed my cravings for sugar and junk food
Cons
- Gave me severe gastrointestinal side effects
- Naltrexone and Bupropion combination can affect mental health
- Expensive over time since it’s a subscription
Final Thoughts
After eight weeks on Hers Weight Loss, I can confidently say that this program does have potential, but it’s not for everyone.
If you’re someone who struggles with uncontrollable cravings or emotional eating, it might truly help you break that cycle. But if you’re sensitive to medications, prone to anxiety, or value your mental clarity above all else, tread carefully.
For me, losing four pounds wasn’t worth losing my spark.
I appreciate that Hers offers medical supervision and accessibility, but I wish there was more transparency about the emotional and physical toll these medications can take. It’s not just about appetite. It’s about how you feel in your own skin, mind, and mood.
Would I continue? Probably not, unless the brain fog completely lifts. But I’ll say this. It taught me a lot about my body, my relationship with food, and the importance of researching what I put in my body.
If you’re considering Hers, go in informed, talk to your doctor, and most importantly, listen to your body.
while you’re here, read my review of Kind Patches GLP -1. The fad weight loss patches I tried some months back.
